Which action is essential when handling contaminated materials?

Placing contaminated materials into a large plastic bag and sealing it is essential for several reasons. This action helps prevent the spread of infection and protects both healthcare workers and other patients from potential exposure to hazardous substances. Sealing the bag ensures that no contaminants can escape during transport or disposal, which is critical in maintaining a safe and clean environment.

Additionally, using a specific type of bag designed for contaminated materials ensures that they are handled according to established safety protocols and regulations, which is important for infection control practices. By properly sealing and disposing of these materials, healthcare providers can help minimize the risk of cross-contamination and ensure compliance with health and safety guidelines.